Rationalization may improve predictability rather than accuracy
نویسندگان
چکیده
منابع مشابه
Most Ligand-Based Benchmarks Measure Overfitting Rather than Accuracy
Undetected overfitting can occur when there are significant redundancies between training and validation data. We describe AVE, a new measure of training-validation redundancy for ligand-based classification problems that accounts for the similarity amongst inactive molecules as well as active. We investigated nine widely-used benchmarks for virtual screening and QSAR, and show that the amount ...
متن کاملDeprenyl Can Mediate Neuronal Protection Rather than Neuronal Rescue
Background and Objective: Deprenyl is a drug for the treatment of Parkinson’s disease, where the dopaminergic neurons are the target of this drug. Several reports also documented that deprenyl has an effect on the sensory and motor neurons. There are some reports about the mode of action of deprenyl on m...
متن کاملMeasurement of Phospholipids May Improve Diagnostic Accuracy in Ovarian Cancer
BACKGROUND More than two-thirds of women who undergo surgery for suspected ovarian neoplasm do not have cancer. Our previous results suggest phospholipids as potential biomarkers of ovarian cancer. In this study, we measured the serum levels of multiple phospholipids among women undergoing surgery for suspected ovarian cancer to identify biomarkers that better predict whether an ovarian mass is...
متن کاملPerihemorheology rather than parahemorheology.
However, the use of the term parahemorheology has been criticized, because the prefix para implies that the rheology of fluids and structures in the perivascular spaces is secondary and less important than that of the vessel-blood organ. It is also imprecise, once it does not refer to the fluids and structures being considered. By contrast, the term perihemorheology implies the rheology of flui...
متن کاملSimplicity Rather Than Knowledge
I’ve spent over 20 years implementing algorithms for Boolean minimization, with particular application to area optimization of large semiconductor circuits. This exploration has included almost all published algorithms, dozens of conventional and exotic data structures, over two dozen programming languages and styles, and almost every level of implementation, from reconfigurable silicon through...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Behavioral and Brain Sciences
سال: 2020
ISSN: 0140-525X,1469-1825
DOI: 10.1017/s0140525x19002279